Views: 1 Author: Site Editor Publish Time: 2022-04-01 Origin: Site
Immunity is the "umbrella" of human health. A sudden outbreak has also sounded the alarm for national health awareness. While focusing on external epidemic prevention, people began to pay attention to how to improve their immunity to prevent COVID-19.
With the normalization of the epidemic today, how can people improve their immunity? In short, a reasonable diet, adequate sleep, appropriate exercise and good living habits can improve human immunity. People will choose to supplement some additional nutrients to maintain good health and better resist the invasion of the virus.
On September 13, 2021, researchers from Charlotte Medical College in Berlin, Germany published a research paper entitled virus induced sensitivity is driver and therapeutic target in covid-19 in nature. This is a peer-reviewed review study on the inducement and therapeutic target of cell senescence caused by new crown. Quercetin, an excellent plant active ingredient, has been mentioned many times in this study, It has the effect of preventing COVID-19 and reducing the new crown.
Quercetin is a kind of flavonoids with a variety of biological activities, which is widely distributed in the plant world.
Quercetin exists in the flowers, leaves and fruits of many plants. Modern medical research has proved that quercetin has a variety of biological activities, such as antioxidant and free radical scavenging, anti-inflammatory, anti-virus, cardiovascular protection, immune regulation and so on.
However, due to its poor water solubility, fast metabolism and short half-life, quercetin has low bioavailability, which limits its application. Therefore, the bioavailability of quercetin after oral administration has become a major concern.
Antiviral and immunomodulatory effects of Quercetin
Quercetin achieves antiviral effect by blocking virus fusion, inhibiting virus gene transcription and inhibiting protein expression of infected cells, and plays an immunomodulatory role by inhibiting lymphocyte activation and proliferation. Because of its broad-spectrum antiviral and immunomodulatory effects, and high human tolerance, it has very important clinical significance for virus infection and immune system diseases, and has attracted more and more attention.
As early as 2010, there was a randomized, double-blind, placebo-controlled trial (12 weeks for 1002 adults aged 18 to 85). The analysis of healthy subjects over the age of 40 showed that the severity and total days of upper respiratory tract infection in the 1000 mg quercetin daily supplement group were lower than those in the placebo group. This shows that quercetin supplementation can prevent upper respiratory tract infection for middle-aged and elderly people in good health. In addition, a large number of studies have emphasized the ability of quercetin to prevent and treat the common cold and influenza. Therefore, novel coronavirus pneumonia may be helpful for preventing and treating new crown pneumonia infection.