Views: 4 Author: Site Editor Publish Time: 2022-07-15 Origin: Site
Senna is a shrub that grows in India, Pakistan, southern China and many other places. Its name is derived from the Arabic word "Sena" and has been used in ancient Indian and Greek medicine since the 9th century. The shrub can grow to about two feet tall, with green stems, pods and yellow spade shaped leaves. Its alternate leaves are evergreen, with four to five pairs of lanceolate or obovate gray green fragile leaflets. Flowers small, yellow, with five clawed irregular petals. The fruit is wrapped in a rectangular pod about 5cm long. Leaves and pods or fruits can be used medicinally.
Senna leaf, synonymous with zhana leaf, senna leaf and bubble bamboo leaf, comes from the leaflets of narrow leaf Senna or sharp leaf Senna of legumes. The English name is Folium Sennae, an irritant laxative, which stimulates intestinal peristalsis through intestinal mucosa and nerves. It is a powerful drug, and it is recommended to use it as little as possible. Acting on colon, it usually takes effect within a few hours.
People in northern Africa and southwest Asia have used Senna as a laxative for centuries. Senna is traditionally considered as a "clean" herb because of its cathartic properties. More modern studies have found that Senna is very effective in treating constipation, whether caused by drugs or naturally. In addition, its leaves are sometimes made into paste and used in a variety of skin diseases. Tinea and acne can be treated with this method.
Senna is native to dry and hot areas. It only takes 3-5 months from sowing to flowering and fruiting. The average temperature suitable for growth should be lower than 10 ℃ for 180-200 days, and the accumulated temperature in this period should not be less than 4000-4500 ℃. In Yuanjiang County, Yunnan Province, which is relatively dry and hot in China, the annual average temperature is 23.8 ℃, and the annual rainfall is 484.7mm. The introduction and growth are good. The soil requires loose, well drained sandy soil or alluvial soil, and the soil is slightly acidic or neutral.
Senna leaf contains sennoside C, namely Rhein aloe emodin dianthrone-8,8 '- diglucoside. Besides sennoside A and B, the pods also contain glucosides of rhein and chrysophanol, and trace aloe emodin or emodin glucoside. Senna acuminata and legume contain 0.85 ~ 2.86% and 2.34 ~ 3.16% of the components, respectively, from which rhein, aloe emodin, a small amount of chrysophanol and sennoside a, B, C and other sennoside are separated. These anthracene components exist as glycosides. This plant also contains 3,5-dimethyl-4-methoxybenzoic acid. The same plant, senna auricula, contains tannin, leaves contain anthocyanins, and bark contains polyphenol oxidase.
The active ingredient in senna leaf is called sennoside. This component molecule is converted by microorganisms into another substance in the colon, anthrone rhein, which has beneficial effects on stimulating colon activity (which accelerates intestinal peristalsis and improves digestion) and increasing fluid secretion. The laxative effect of sennoside and its active metabolite anthraquinone Rhein are believed to inhibit the absorption of water and electrolyte in the large intestine, thereby increasing the volume and pressure of intestinal contents. It will stimulate the pushing contraction movement of the colon. In addition, the stimulating effect on the secretion of active chloride increases the content of intestinal water and electrolyte. These changes in the transport of active electrolyte depend on the calcium element on the slurry surface. The laxative effect of sennoside is partly through the stimulation of colonic fluid and electrolyte secretion, and this secretion ability is regulated by the stimulation of endogenous prostaglandin formation. Sennoside can be prepared into enema or suppository or mixed with stool softener or bulky fiber laxative to form a combined laxative.
Sennoside is a powerful laxative, so you should take it carefully and pay attention to the dosage. Especially for pregnant, menstrual or postpartum women. Because it is irritant, it cannot be used in patients with gastrointestinal inflammation. This irritant effect on intestinal mucosa may cause irritation, pain or nausea, and liquid feces or diarrhea in case of overdose.
Senna leaf contains: about 3% of double anthrone glycosides (sennoside a, A1, B, C, D, e, F and G); And a small amount of anthraquinones, including aloe emodin and rhein-8-glucoside; About 10% mucilage, tannins and flavonoids. The extract standard contains 8% sennoside. The product is mainly composed of sennoside.
Senna leaf has the following functions: Purging Heat and stagnation, catharsis, and diuresis. For heat stagnation, constipation, abdominal pain, edema and fullness.
Senna leaf extract has certain antibacterial function, and can also be used in acute pancreatitis, bacillary dysentery, epidemic hemorrhagic fever, cholecystitis, postpartum lactation, etc. It is suitable for medicine, health products and other fields.