Views: 15 Author: Site Editor Publish Time: 2021-01-27 Origin: Site
1. Cnidium extract is the Apiaceae plant Cnidium
The dry ripe fruit of Cnidium monnieri. Cnidium is anannual herb. It loves a warm, humid environment, is not afraid of severe cold and drought, and has wide adaptability. It is distributed in East China, Central and South my country.
2. Product specifications
Osthole 98% Osthole 20%
3. Efficacy and application
1). External use
Osthole has an inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and can also weaken the pathogenicity of residual Staphylococcus aureus strains. It can be used in conjunction with matrine to treat trichomonas vaginitis, eczema, psoriasis, etc.
Osthole has an inhibitory effect on Staphylococcus aureus and has a good effect on bacterial inflammation. Osthol and baicalin are used in combination to treat pneumonia caused by Staphylococcus aureus.
Osthole can inhibit tumor growth in mouse liver cancer models, and it can also induce apoptosis of liver cancer cells through multiple targets and multiple pathways, and enhance the anti-tumor immune response of liver cancer mice; Osthole can also injure nasopharyngeal cancer cells , Lung cancer cells and cervical cancer cells, etc., have inhibitory effects on the growth of a variety of tumor cells. Can be used to help fight cancer.
Osthole can significantly promote the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblasts.
At the same time, it significantly increases the expression levels of osteocalcin and alkaline phosphatase, thereby promoting bone formation, increasing bone mineral content and bone strength.
Osthole promotes the proliferation and differentiation of osteoblasts and is related to the concentration, the best concentration is between 5*10-5M-5*10-4M. In addition, osthol and puerarin can be used together to treat bone dysplasia and osteoporosis.
Effects on the endocrine system
Osthole can promote the synthesis and secretion of androgen in testicular stromal cells by regulating the gene transcription of related enzymes and their cell membrane and cytoplasm-related receptors in the process of androgen synthesis in mouse testicular stromal cells;
It can also increase the content of testosterone, follicle stimulating hormone, and luteinizing hormone in the serum, with androgen-like effects and gonadotropin-like effects; and osthole at 40-80μg/mL can effectively alleviate the oxidation caused by H2O2 in ovarian tissue Stress damage protects the function of ovarian tissue and enhances its antioxidant capacity.
◎ Used insurgical lotion, such as Fuyanjie.
◎ Used for surgical skin diseases, compound treatment of psoriasis, eczema, etc.
◎ Used for bone dysplasia and osteoporosis of the elderly.
◎ Used to regulate endocrine disorders, compound treatment of infertility, etc.
◎ It can be used to remove lice from animals and biological pesticides of plant origin.