Views: 4 Author: Site Editor Publish Time: 2023-03-23 Origin: Site
Codonopsis is the dried root of Codonopsis Codonopsis, Suhua Codonopsis and Sichuan Codonopsis, which are commonly used tonic Chinese medicines. Codonopsis pilosula has complex phytochemical components.So far, domestic and foreign scholars have isolated and identified more than 230 compounds from Codonopsis genus, including alkaloids,acetylenes, terpenes, flavonoids, lignin, steroids, sugars and other components.Among them, alkaloids, polyacetylenes, lignans, flavonoids and polysaccharides are considered as the main active ingredients.Codonopsis pilosula has rich and diverse pharmacological effects, mainly acting on the nervous system, endocrine system, and immune system.A large number of studies have found that Codonopsis pilosula has the functions of protecting nerves, anti-tumor, anti-oxidation,anti-inflammation, anti-stress,and protecting the liver.
1.Protection of the nervous system
Codonopsis pilosula extract has neuroprotective effects such as protecting nerve cells, improving learning and memory ability, and alleviating the symptoms of Alzheimer's disease (AD).
2.Regulate blood sugar and blood lipids
Codonopsis pilosula extract has the function of regulating blood sugar and blood lipid.Codonopsis pilosula water extract can lower blood sugar, inhibit the activity of aldose reductase,and delay the progress of diabetes.Codonopsis total saponins can reduce serum total cholesterol,triacylglycerol, and low-density lipoprotein cholesterol in hyperlipidemic rats, increase NO and high-density lipoprotein cholesterol, and have the effect of regulating blood lipids.
3.The effect on the immune system
Codonopsis pilosula has the function of regulating the immune balance of the body.
4.Effects on the digestive system
Codonopsis pilosula extract has pharmacological effects such as treating gastric ulcer, promoting intestinal tract movement, and improving the body's digestion ability.Codonopsis polysaccharides can increase the thickness of gastric mucosa and gastric wall, promote the growth of intestinal villi, promote intestinal peristalsis, improve digestion, and regulate the intestinal flora of colitis mice. Codonopsis inulin-type fructan can improve gastrointestinal function by changing the composition and metabolism of intestinal microbiota. It is a potential prebiotic and a potential component for the treatment of acute gastric ulcer.
5.Effect on blood circulation
Codonopsis pilosula extract has the effects of treating heart failure, regulating the growth and development of blood cells, enhancing hematopoietic function,and inhibiting platelet aggregation.
Modern studies have found that Codonopsis pilosula has antibacterial and antiviral effects.In vitro antibacterial experiments found that the ethanol extract of Codonopsis pilosula had significant inhibitory effects on common bacteria such as Staphylococcus aureus, Bacillus subtilis,Bacillus anthracis,Escherichia coli, and Salmonella typhi.Codonopsis polysaccharide can reduce the expression level of IFN-β and inhibit the virulence of duck hepatitis A virus.