Views: 12 Author: Site Editor Publish Time: 2021-03-25 Origin: Site
1. External use
Antibacterial —— Osthole has an inhibitory effect on Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli, and can also reduce the pathogenicity of residual Staphylococcus aureus strains. It can be used in conjunction with matrine to treat trichomonas vaginitis, eczema, psoriasis, etc.
Anti-inflammatory-Osthole has an inhibitory effect on Staphylococcus aureus and has a good effect on bacterial inflammation. Osthole and baicalin are used in combination to treat pneumonia caused by Staphylococcus aureus.
Anti-cancer-Osthole can inhibit tumor growth in mouse liver cancer models, and can also induce apoptosis of liver cancer cells through multiple targets and multiple pathways, and enhance the anti-tumor immune response of liver cancer mice; Osthole can also kill Nasopharyngeal cancer cells, lung cancer cells and cervical cancer cells have inhibitory effects on the growth of a variety of tumor cells. Can be used to help fight cancer.
Anti-osteoporosis-Osthole can significantly promote the proliferation and differentiation of bone marrow mesenchymal stem cells and osteoblasts, and at the same time significantly increase the expression levels of osteocalcin and alkaline phosphatase, thereby promoting bone formation and increasing bone mineral content And bone strength. Osthole promotes the proliferation and differentiation of osteoblasts and is related to the concentration, the best concentration is between 5*10-5M-5*10-4M. In addition, osthole and puerarin can be used together to treat bone dysplasia and osteoporosis.Effects on the endocrine system-Osthole can promote the synthesis and secretion of androgen in testicular stromal cells by regulating the gene transcription of related enzymes and their cell membranes and cytoplasm-related receptors in the process of androgen synthesis in mouse testicular stromal cells; It can also increase the content of testosterone, follicle stimulating hormone, and luteinizing hormone in the serum, with androgen-like effects and gonadotropin-like effects; and osthole at 40-80μg/mL can effectively alleviate the oxidation caused by H2O2 in ovarian tissue Stress damage protects the function of ovarian tissue and enhances the antioxidant capacity of ovarian tissue.
3. Biological pesticides
Osthole with low content can be used as a plant-derived insecticide, a protective agent for stored grains, etc. Moreover, as a pesticide, Osthol has passed the organic certification and can be used in organic product bases. 1% Osthole Water Emulsion has a special effect on melons, strawberries, flowers and powdery mildew (the prevention efficiency is about 95%), and it has a combined effect on vegetable downy mildew and aphids. 4% Osthole powder has a good control effect on corn weevil, dù and adult worms. Compared with other plant-derived insecticides, Osthole has the advantages of high efficiency and low toxicity.
Proportional extract (can be detected by TLC)